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A prospective 3-year follow-up trial of implantation of two trabecular microbypass stents in open-angle glaucoma

Overview of attention for article published in Clinical Ophthalmology, November 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

twitter
3 tweeters
facebook
1 Facebook page

Citations

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54 Dimensions

Readers on

mendeley
45 Mendeley
Title
A prospective 3-year follow-up trial of implantation of two trabecular microbypass stents in open-angle glaucoma
Published in
Clinical Ophthalmology, November 2015
DOI 10.2147/opth.s91732
Pubmed ID
Authors

Jane Ellen Giamporcaro, Kerry Solomon, Lilit Voskanyan, David Chang, Thomas Samuelson, Iqbal Ike Ahmed, L. Jay Katz, Eric Donnenfeld

Abstract

To evaluate 3-year safety and intraocular pressure (IOP) following two trabecular microbypass stents in phakic and pseudophakic subjects with open-angle glaucoma (OAG) not controlled on preoperative medication. In this prospective pilot study, phakic or pseudophakic subjects with OAG and IOP between 18 mmHg and 30 mmHg on one preoperative topical ocular hypotensive medication underwent medication washout. Thirty-nine qualified subjects with preoperative unmedicated IOP ≥22 mmHg and ≤38 mmHg received two stents. Postoperative examinations were scheduled at Day 1, Week 1, Months 1, 3, 6, and 12, and semiannually through Month 60. Ocular hypotensive medication was considered if postoperative IOP exceeded 21 mmHg. IOP, medication use, and safety were assessed at each visit. Subject follow-up through Month 36 was completed. Thirty-six eyes (92.3%; 95% confidence interval [CI] 79.1%, 98.4%) achieved the primary efficacy end point of Month 12 reduction in IOP ≥20% from baseline (unmedicated IOP) without ocular hypotensive medication. Four subjects required medication during the Month 36 follow-up period. Mean IOP at 36 months for subjects not taking medication was 15.2 mmHg. At 36 months, subjects sustained mean IOP decrease of 9.1±2.7 mmHg (95% CI 8.0 mmHg, 10.14 mmHg), or 37% IOP reduction, from unmedicated baseline IOP. Compared to preoperative medicated IOP, subjects had mean reduction at Month 36 of 5.5±2.7 mmHg (95% CI 4.5 mmHg, 6.6 mmHg), or 26% reduction. Both measures of IOP reduction were highly significant (P<0.001). Other than one case of early postoperative hyphema that resolved at 1 week, no postoperative adverse events were attributed to stent implantation. In a pilot study, two trabecular microbypass stents to treat OAG subjects on one preoperative medication provided statistically significant, sustained, and safe reduction of IOP to ≤15 mmHg without medication through 36 months.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
New Zealand 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Other 7 16%
Student > Master 7 16%
Student > Bachelor 6 13%
Student > Ph. D. Student 6 13%
Student > Doctoral Student 3 7%
Other 8 18%
Unknown 8 18%
Readers by discipline Count As %
Medicine and Dentistry 28 62%
Agricultural and Biological Sciences 3 7%
Biochemistry, Genetics and Molecular Biology 2 4%
Business, Management and Accounting 1 2%
Computer Science 1 2%
Other 3 7%
Unknown 7 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2015.
All research outputs
#13,215,982
of 22,832,057 outputs
Outputs from Clinical Ophthalmology
#955
of 3,188 outputs
Outputs of similar age
#130,934
of 284,444 outputs
Outputs of similar age from Clinical Ophthalmology
#29
of 73 outputs
Altmetric has tracked 22,832,057 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,188 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,444 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.