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Cognitive dysfunction in bipolar disorder and schizophrenia: a systematic review of meta-analyses

Overview of attention for article published in Neuropsychiatric Disease and Treatment, December 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

twitter
10 tweeters
facebook
3 Facebook pages
wikipedia
1 Wikipedia page

Citations

dimensions_citation
103 Dimensions

Readers on

mendeley
225 Mendeley
Title
Cognitive dysfunction in bipolar disorder and schizophrenia: a systematic review of meta-analyses
Published in
Neuropsychiatric Disease and Treatment, December 2015
DOI 10.2147/ndt.s76700
Pubmed ID
Authors

André F Carvalho, Beatrice Bortolato, Kamilla Miskowiak, Eduard Vieta, Cristiano Köhler

Abstract

Cognitive impairment is a core feature of schizophrenia (SZ) and bipolar disorder (BD). A neurocognitive profile characterized by widespread cognitive deficits across multiple domains in the context of substantial intellectual impairment, which appears to antedate illness onset, is a replicated finding in SZ. There is no specific neuropsychological signature that can facilitate the diagnostic differentiation of SZ and BD, notwithstanding, neuropsychological deficits appear more severe in SZ. The literature in this field has provided contradictory results due to methodological differences across studies. Meta-analytic techniques may offer an opportunity to synthesize findings and to control for potential sources of heterogeneity. Here, we performed a systematic review of meta-analyses of neuropsychological findings in SZ and BD. While there is no conclusive evidence for progressive cognitive deterioration in either SZ or BD, some findings point to more severe cognitive deficits in patients with early illness onset across both disorders. A compromised pattern of cognitive functioning in individuals at familiar and/or clinical risk to psychosis as well as in first-degree relatives of BD patients suggests that early neurodevelopmental factors may play a role in the emergence of cognitive deficits in both disorders. Premorbid intellectual impairment in SZ and at least in a subgroup of patients with BD may be related to a shared genetically determined influence on neurodevelopment.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 225 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 <1%
Lithuania 1 <1%
Denmark 1 <1%
Nigeria 1 <1%
Spain 1 <1%
Unknown 220 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 36 16%
Researcher 33 15%
Student > Ph. D. Student 31 14%
Student > Bachelor 29 13%
Student > Postgraduate 17 8%
Other 46 20%
Unknown 33 15%
Readers by discipline Count As %
Psychology 67 30%
Medicine and Dentistry 49 22%
Neuroscience 27 12%
Nursing and Health Professions 7 3%
Agricultural and Biological Sciences 5 2%
Other 16 7%
Unknown 54 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2018.
All research outputs
#1,853,119
of 14,535,828 outputs
Outputs from Neuropsychiatric Disease and Treatment
#306
of 2,442 outputs
Outputs of similar age
#46,393
of 320,417 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#7
of 65 outputs
Altmetric has tracked 14,535,828 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,442 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,417 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.