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Effect of caffeic acid phenethyl ester on bone formation in the expanded inter-premaxillary suture

Overview of attention for article published in Drug Design, Development and Therapy, December 2015
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Title
Effect of caffeic acid phenethyl ester on bone formation in the expanded inter-premaxillary suture
Published in
Drug Design, Development and Therapy, December 2015
DOI 10.2147/dddt.s97797
Pubmed ID
Authors

Hakki Oguz Kazancioglu, Sertac Aksakalli, Seref Ezirganli, Muhammet Birlik, Mukaddes Esrefoglu, Ahmet Hüseyin Acar

Abstract

Narrow maxilla is a common problem in orthodontics and dentofacial orthopedics. To solve this problem, a procedure called rapid maxillary expansion (RME) has been used. However, relapse tendency is a major problem of RME. Although relapse tendency is not clearly understood, various treatment procedures and new applications have been investigated. The present study aimed to investigate the possible effectiveness of caffeic acid phenethyl ester (CAPE) on new bone formation in rat midpalatal suture after RME. Twenty male Sprague Dawley rats were used in this study. The animals were randomly divided into two groups as control and CAPE group. In the CAPE group, CAPE was administered systemically via intraperitoneal injection. RME procedure was performed on all animals. For this purpose, the springs were placed on the maxillary incisors of rats and activated for 5 days. After then, the springs were removed and replaced with short lengths of rectangular retaining wire for consolidation period of 15 days. At the end of the study, histomorphometric analysis was carried out to assess new bone formation. New bone formation was significantly greater in the CAPE group than the control group (P<0.05). CAPE enhances new bone formation in midpalatal suture after RME. These results show that CAPE may decrease the time needed for retention.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 29%
Student > Master 4 14%
Other 3 11%
Student > Doctoral Student 3 11%
Student > Postgraduate 3 11%
Other 6 21%
Unknown 1 4%
Readers by discipline Count As %
Medicine and Dentistry 15 54%
Agricultural and Biological Sciences 4 14%
Arts and Humanities 1 4%
Business, Management and Accounting 1 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 2 7%
Unknown 4 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2015.
All research outputs
#5,899,576
of 6,886,791 outputs
Outputs from Drug Design, Development and Therapy
#608
of 918 outputs
Outputs of similar age
#242,531
of 298,544 outputs
Outputs of similar age from Drug Design, Development and Therapy
#62
of 83 outputs
Altmetric has tracked 6,886,791 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 918 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,544 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.