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Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery

Overview of attention for article published in Drug Design, Development and Therapy, January 2016
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Mentioned by

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1 tweeter

Citations

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280 Dimensions

Readers on

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584 Mendeley
Title
Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery
Published in
Drug Design, Development and Therapy, January 2016
DOI 10.2147/dddt.s99651
Pubmed ID
Authors

Tarek Ahmed, Bader Aljaeid

Abstract

Naturally occurring polymers, particularly of the polysaccharide type, have been used pharmaceutically for the delivery of a wide variety of therapeutic agents. Chitosan, the second abundant naturally occurring polysaccharide next to cellulose, is a biocompatible and biodegradable mucoadhesive polymer that has been extensively used in the preparation of micro-as well as nanoparticles. The prepared particles have been exploited as a potential carrier for different therapeutic agents such as peptides, proteins, vaccines, DNA, and drugs for parenteral and nonparenteral administration. Therapeutic agent-loaded chitosan micro- or nanoparticles were found to be more stable, permeable, and bioactive. In this review, we are highlighting the different methods of preparation and characterization of chitosan micro- and nanoparticles, while reviewing the pharmaceutical applications of these particles in drug delivery. Moreover, the roles of chitosan derivatives and chitosan metal nanoparticles in drug delivery have been illustrated.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 584 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
France 1 <1%
Unknown 582 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 102 17%
Student > Ph. D. Student 98 17%
Student > Bachelor 84 14%
Researcher 55 9%
Student > Doctoral Student 37 6%
Other 82 14%
Unknown 126 22%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 97 17%
Chemistry 74 13%
Biochemistry, Genetics and Molecular Biology 55 9%
Agricultural and Biological Sciences 53 9%
Engineering 36 6%
Other 109 19%
Unknown 160 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 January 2016.
All research outputs
#6,067,915
of 7,059,888 outputs
Outputs from Drug Design, Development and Therapy
#623
of 935 outputs
Outputs of similar age
#262,741
of 319,092 outputs
Outputs of similar age from Drug Design, Development and Therapy
#63
of 90 outputs
Altmetric has tracked 7,059,888 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 935 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,092 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.