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Fuchs endothelial corneal dystrophy: current perspectives

Overview of attention for article published in Clinical Ophthalmology, February 2016
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1 tweeter

Citations

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Readers on

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102 Mendeley
Title
Fuchs endothelial corneal dystrophy: current perspectives
Published in
Clinical Ophthalmology, February 2016
DOI 10.2147/opth.s83467
Pubmed ID
Authors

Albert Jun, Gustavo Vedana, Guadalupe Villarreal Jr.

Abstract

Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and frequently results in vision loss. Hallmarks of the disease include loss of corneal endothelial cells and formation of excrescences of Descemet's membrane. Later stages involve all layers of the cornea. Impairment of endothelial barrier and pump function and cell death from oxidative and unfolded protein stress contribute to disease progression. The genetic basis of FECD includes numerous genes and chromosomal loci, although alterations in the transcription factor 4 gene are associated with the majority of cases. Definitive treatment of FECD is corneal transplantation. In this paper, we highlight advances that have been made in understanding FECD's clinical features, pathophysiology, and genetics. We also discuss recent advances in endothelial keratoplasty and potential future treatments.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Colombia 1 <1%
Unknown 99 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 20%
Other 15 15%
Student > Bachelor 13 13%
Student > Master 13 13%
Student > Ph. D. Student 9 9%
Other 20 20%
Unknown 12 12%
Readers by discipline Count As %
Medicine and Dentistry 43 42%
Biochemistry, Genetics and Molecular Biology 20 20%
Agricultural and Biological Sciences 8 8%
Nursing and Health Professions 5 5%
Veterinary Science and Veterinary Medicine 2 2%
Other 8 8%
Unknown 16 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2016.
All research outputs
#9,995,744
of 12,488,808 outputs
Outputs from Clinical Ophthalmology
#1,036
of 1,597 outputs
Outputs of similar age
#188,102
of 269,984 outputs
Outputs of similar age from Clinical Ophthalmology
#50
of 63 outputs
Altmetric has tracked 12,488,808 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,597 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,984 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.