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Current knowledge on psoriasis and autoimmune diseases

Overview of attention for article published in Psoriasis : Targets and Therapy, February 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)

Mentioned by

twitter
9 tweeters
patent
1 patent
facebook
2 Facebook pages

Citations

dimensions_citation
75 Dimensions

Readers on

mendeley
289 Mendeley
Title
Current knowledge on psoriasis and autoimmune diseases
Published in
Psoriasis : Targets and Therapy, February 2016
DOI 10.2147/ptt.s64950
Pubmed ID
Authors

Thomas McCormick, Nilmarie Ayala-Fontanez, David Soler

Abstract

Psoriasis is a prevalent, chronic inflammatory disease of the skin, mediated by crosstalk between epidermal keratinocytes, dermal vascular cells, and immunocytes such as antigen presenting cells (APCs) and T cells. Exclusive cellular "responsibility" for the induction and maintenance of psoriatic plaques has not been clearly defined. Increased proliferation of keratinocytes and endothelial cells in conjunction with APC/T cell/monocyte/macrophage inflammation leads to the distinct epidermal and vascular hyperplasia that is characteristic of lesional psoriatic skin. Despite the identification of numerous susceptibility loci, no single genetic determinant has been identified as responsible for the induction of psoriasis. Thus, numerous other triggers of disease, such as environmental, microbial and complex cellular interactions must also be considered as participants in the development of this multifactorial disease. Recent advances in therapeutics, especially systemic so-called "biologics" have provided new hope for identifying the critical cellular targets that drive psoriasis pathogenesis. Recent recognition of the numerous co-morbidities and other autoimmune disorders associated with psoriasis, including inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematosus suggest common signaling elements and cellular mediators may direct disease pathogenesis. In this review, we discuss common cellular pathways and participants that mediate psoriasis and other autoimmune disorders that share these cellular signaling pathways.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 289 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 288 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 41 14%
Student > Bachelor 38 13%
Student > Ph. D. Student 31 11%
Researcher 24 8%
Student > Doctoral Student 24 8%
Other 61 21%
Unknown 70 24%
Readers by discipline Count As %
Medicine and Dentistry 83 29%
Biochemistry, Genetics and Molecular Biology 40 14%
Pharmacology, Toxicology and Pharmaceutical Science 18 6%
Agricultural and Biological Sciences 17 6%
Nursing and Health Professions 12 4%
Other 39 13%
Unknown 80 28%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2021.
All research outputs
#2,353,819
of 17,733,079 outputs
Outputs from Psoriasis : Targets and Therapy
#10
of 57 outputs
Outputs of similar age
#45,056
of 272,193 outputs
Outputs of similar age from Psoriasis : Targets and Therapy
#1
of 1 outputs
Altmetric has tracked 17,733,079 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 57 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 272,193 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them