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Medical management of epileptic seizures: challenges and solutions

Overview of attention for article published in Neuropsychiatric Disease and Treatment, February 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
3 tweeters
facebook
4 Facebook pages

Citations

dimensions_citation
9 Dimensions

Readers on

mendeley
72 Mendeley
Title
Medical management of epileptic seizures: challenges and solutions
Published in
Neuropsychiatric Disease and Treatment, February 2016
DOI 10.2147/ndt.s80586
Pubmed ID
Authors

Gretchen M. Brophy, Anand Sarma, Nabil Khandker, Lisa Kurczewski

Abstract

Epilepsy is one of the most common neurologic illnesses. This condition afflicts 2.9 million adults and children in the US, leading to an economic impact amounting to $15.5 billion. Despite the significant burden epilepsy places on the population, it is not very well understood. As this understanding continues to evolve, it is important for clinicians to stay up to date with the latest advances to provide the best care for patients. In the last 20 years, the US Food and Drug Administration has approved 15 new antiepileptic drugs (AEDs), with many more currently in development. Other advances have been achieved in terms of diagnostic modalities like electroencephalography technology, treatment devices like vagal nerve and deep-brain stimulators, novel alternate routes of drug administration, and improvement in surgical techniques. Specific patient populations, such as the pregnant, elderly, those with HIV/AIDS, and those with psychiatric illness, present their own unique challenges, with AED side effects, drug interactions, and medical-psychiatric comorbidities adding to the conundrum. The purpose of this article is to review the latest literature guiding the management of acute epileptic seizures, focusing on the current challenges across different practice settings, and it discusses studies in various patient populations, including the pregnant, geriatric, those with HIV/AIDS, comatose, psychiatric, and "pseudoseizure" patients, and offers possible evidence-based solutions or the expert opinion of the authors. Also included is information on newer AEDs, routes of administration, and significant AED-related drug-interaction tables. This review has tried to address only some of these issues that any practitioner who deals with the acute management of seizures may encounter. The document also highlights the numerous avenues for new research that would help practitioners optimize epilepsy management.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 72 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 25%
Student > Bachelor 10 14%
Student > Ph. D. Student 9 13%
Other 8 11%
Researcher 8 11%
Other 13 18%
Unknown 6 8%
Readers by discipline Count As %
Medicine and Dentistry 20 28%
Nursing and Health Professions 9 13%
Psychology 8 11%
Pharmacology, Toxicology and Pharmaceutical Science 6 8%
Biochemistry, Genetics and Molecular Biology 5 7%
Other 17 24%
Unknown 7 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2016.
All research outputs
#7,504,729
of 14,533,317 outputs
Outputs from Neuropsychiatric Disease and Treatment
#871
of 2,427 outputs
Outputs of similar age
#100,314
of 267,564 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#46
of 75 outputs
Altmetric has tracked 14,533,317 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,427 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,564 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.