Title |
Suvorexant: a promising, novel treatment for insomnia
|
---|---|
Published in |
Neuropsychiatric Disease and Treatment, February 2016
|
DOI | 10.2147/ndt.s31495 |
Pubmed ID | |
Authors |
Joyce K Lee-Iannotti, James M Parish |
Abstract |
Suvorexant a novel, orexin receptor antagonist was recently approved by the US Food and Drug Administration for the treatment of sleep onset and sleep maintenance insomnia in August 2014. Multiple animal and human studies support the efficacy, safety, and tolerability of suvorexant for patients of various profiles. Current recommendations advocate for a starting dose of 10 mg and a maximum dose of 20 mg, with cautious use in women, obese patients, and patients taking other CYP3A4 inhibitors. More head-to-head studies comparing suvorexant to other sedative-hypnotic therapies are needed to further delineate which patients will benefit the most from this medication over others. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 2 | 50% |
Members of the public | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 56 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 20% |
Researcher | 6 | 11% |
Student > Master | 5 | 9% |
Student > Doctoral Student | 4 | 7% |
Other | 4 | 7% |
Other | 7 | 13% |
Unknown | 19 | 34% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 11% |
Agricultural and Biological Sciences | 5 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Neuroscience | 3 | 5% |
Other | 5 | 9% |
Unknown | 27 | 48% |