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Dove Medical Press

Antimicrobial performance of mesoporous titania thin films: role of pore size, hydrophobicity, and antibiotic release

Overview of attention for article published in International Journal of Nanomedicine, March 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

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Citations

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51 Mendeley
Title
Antimicrobial performance of mesoporous titania thin films: role of pore size, hydrophobicity, and antibiotic release
Published in
International Journal of Nanomedicine, March 2016
DOI 10.2147/ijn.s95375
Pubmed ID
Authors

Saba Atefyekta, Batur Ercan, Johan Karlsson, Erik Taylor, Stanley Chung, Thomas J Webster, Martin Andersson

Abstract

Implant-associated infections are undesirable complications that might arise after implant surgery. If the infection is not prevented, it can lead to tremendous cost, trauma, and even life threatening conditions for the patient. Development of an implant coating loaded with antimicrobial substances would be an effective way to improve the success rate of implants. In this study, the in vitro efficacy of mesoporous titania thin films used as a novel antimicrobial release coating was evaluated. Mesoporous titania thin films with pore diameters of 4, 6, and 7 nm were synthesized using the evaporation-induced self-assembly method. The films were characterized and loaded with antimicrobial agents, including vancomycin, gentamicin, and daptomycin. Staphylococcus aureus and Pseudomonas aeruginosa were used to evaluate their effectiveness toward inhibiting bacterial colonization. Drug loading and delivery were studied using a quartz crystal microbalance with dissipation monitoring, which showed successful loading and release of the antibiotics from the surfaces. Results from counting bacterial colony-forming units showed reduced bacterial adhesion on the drug-loaded films. Interestingly, the presence of the pores alone had a desired effect on bacterial colonization, which can be attributed to the documented nanotopographical effect. In summary, this study provides significant promise for the use of mesoporous titania thin films for reducing implant infections.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 35%
Student > Master 7 14%
Student > Bachelor 5 10%
Student > Doctoral Student 2 4%
Researcher 2 4%
Other 7 14%
Unknown 10 20%
Readers by discipline Count As %
Materials Science 10 20%
Chemistry 8 16%
Engineering 5 10%
Medicine and Dentistry 5 10%
Biochemistry, Genetics and Molecular Biology 3 6%
Other 7 14%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2017.
All research outputs
#7,047,954
of 25,374,917 outputs
Outputs from International Journal of Nanomedicine
#734
of 4,123 outputs
Outputs of similar age
#91,427
of 312,601 outputs
Outputs of similar age from International Journal of Nanomedicine
#19
of 98 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 4,123 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,601 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 98 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.