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Canada acute coronary syndrome score was a stronger baseline predictor than age ≥75 years of in-hospital mortality in acute coronary syndrome patients in western Romania

Overview of attention for article published in Clinical Interventions in Aging, April 2016
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Title
Canada acute coronary syndrome score was a stronger baseline predictor than age ≥75 years of in-hospital mortality in acute coronary syndrome patients in western Romania
Published in
Clinical Interventions in Aging, April 2016
DOI 10.2147/cia.s104943
Pubmed ID
Authors

Antoanela Pogorevici, Ioana Mihaela Citu, Diana Aurora Bordejevic, Florina Caruntu, Mirela Cleopatra Tomescu

Abstract

Several risk scores were developed for acute coronary syndrome (ACS) patients, but their use is limited by their complexity. The purpose of this study was to identify predictors at admission for in-hospital mortality in ACS patients in western Romania, using a simple risk-assessment tool - the new Canada acute coronary syndrome (C-ACS) risk score. The baseline risk of patients admitted with ACS was retrospectively assessed using the C-ACS risk score. The score ranged from 0 to 4; 1 point was assigned for the presence of each of the following parameters: age ≥75 years, Killip class >1, systolic blood pressure <100 mmHg, and heart rate >100 bpm. A total of 960 patients with ACS were included, 409 (43%) with ST-segment elevation myocardial infarction (STEMI) and 551 (57%) with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). The C-ACS score predicted in-hospital mortality in all ACS patients with a C-statistic of 0.95 (95% CI: 0.93-0.96), in STEMI patients with a C-statistic of 0.92 (95% confidence interval [CI]: 0.89-0.94), and in NSTE-ACS patients with a C-statistic of 0.97 (95% CI: 0.95-0.98). Of the 960 patients, 218 (22.7%) were aged ≥75 years. The proportion of patients aged ≥75 years was 21.7% in the STEMI subgroup and 23.4% in the NSTE-ACS subgroup (P>0.05). Age ≥75 years was significantly associated with in-hospital mortality in ACS patients (odds ratio [OR]: 3.25, 95% CI: 1.24-8.25) and in the STEMI subgroup (OR >3.99, 95% CI: 1.28-12.44). Female sex was strongly associated with mortality in the NSTE-ACS subgroup (OR: 27.72, 95% CI: 1.83-39.99). We conclude that C-ACS score was the strongest predictor of in-hospital mortality in all ACS patients while age ≥75 years predicted the mortality well in the STEMI subgroup.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 14%
Student > Bachelor 2 10%
Other 1 5%
Student > Doctoral Student 1 5%
Professor 1 5%
Other 5 24%
Unknown 8 38%
Readers by discipline Count As %
Medicine and Dentistry 10 48%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Agricultural and Biological Sciences 1 5%
Nursing and Health Professions 1 5%
Unknown 8 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2016.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Clinical Interventions in Aging
#1,550
of 1,968 outputs
Outputs of similar age
#234,497
of 314,725 outputs
Outputs of similar age from Clinical Interventions in Aging
#41
of 53 outputs
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