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Correlation between vitamin D levels and muscle fatigue risk factors based on physical activity in healthy older adults

Overview of attention for article published in Clinical Interventions in Aging, January 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

twitter
9 tweeters
facebook
1 Facebook page

Citations

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25 Dimensions

Readers on

mendeley
77 Mendeley
Title
Correlation between vitamin D levels and muscle fatigue risk factors based on physical activity in healthy older adults
Published in
Clinical Interventions in Aging, January 2016
DOI 10.2147/cia.s102892
Pubmed ID
Authors

Sami Gabr, Einas S. Al-Eisa, Ahmad H. Alghadir, Ahmad Alghadir, Al-Eisa, Einas S, Alghadir, Ahmad H, Gabr, Sami A, Ahmad H. Alghadir

Abstract

The purpose of this study was to investigate the relationship of serum vitamin D levels with physical activity, obesity, muscle fatigue biomarkers, and total antioxidant capacity (TAC) in healthy older adults. A total of 85 healthy older subjects aged 64-96 years were recruited in this study. Based on estimated energy expenditure scores, the participants were classified into three groups: inactive (n=25), moderate (n=20), and physically active (n=35). Serum 25(OH)D (25-hydroxy vitamin D) levels, metabolic syndrome parameters, TAC activity, muscle fatigue biomarkers (Ca, creatine kinase, lactic acid dehydrogenase, troponin I, hydroxyproline), physical activity, body fatness, and fatigue score (visual analog scale) were estimated using immunoassay techniques and prevalidated questionnaires, respectively. Physical activity was estimated in 64.6% of the participants. Males showed higher physical activity (42.5%) compared to females (26.25%). Compared to participants with lower activity, significant reduction in body mass index, waist circumference, hips, fasting blood sugar, triglycerides, total cholesterol, HDL-cholesterol, and LDL-cholesterol were observed in moderate and physically active participants. Also, significant increase in the levels of serum 25(OH)D concentrations, calcium, and TAC activity along with reduction in the levels of muscle fatigue biomarkers: creatine kinase, lactic acid dehydrogenase, troponin I, hydroxyproline, and fatigue scores (visual analog scale) were reported in physically active participants compared to those of lower physical activity. In all participants, serum 25(OH)D concentrations correlated positively with Ca, TAC, physical activity scores, and negatively with body mass index, lipid profile, fatigue scores (visual analog scale), and muscle fatigue biomarkers. Stepwise regression analysis showed that serum 25(OH)D concentrations, physical activity, Ca, TAC, and demographic parameters explained approximately 61.4%-85.8% of reduction in both fatigue scores and muscle fatigue biomarkers with substantial improvement in muscle performance in healthy older adults. The data showed that considerable levels of 25(OH)D concentrations, calcium intake, and lower obesity positively correlated with the improvement in the muscle relief and performance of physically active participants. These results demonstrate that 25(OH)D concentrations and calcium might prevent muscle fatigue by regulation of the biosynthesis of creatine kinase, lactic acid dehydrogenase, troponin I, and hydroxyproline via a proposed antifree radical mechanism reported by higher TAC activity. It was suggested that vitamin D status could be reported as a marker of the improvement of muscle performance, especially in healthy older adults with lower physical activity.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Taiwan 1 1%
Unknown 75 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 23%
Student > Ph. D. Student 8 10%
Student > Bachelor 7 9%
Researcher 6 8%
Student > Postgraduate 6 8%
Other 15 19%
Unknown 17 22%
Readers by discipline Count As %
Medicine and Dentistry 18 23%
Nursing and Health Professions 10 13%
Sports and Recreations 8 10%
Agricultural and Biological Sciences 7 9%
Biochemistry, Genetics and Molecular Biology 4 5%
Other 10 13%
Unknown 20 26%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2016.
All research outputs
#1,187,825
of 7,876,706 outputs
Outputs from Clinical Interventions in Aging
#176
of 958 outputs
Outputs of similar age
#59,044
of 267,956 outputs
Outputs of similar age from Clinical Interventions in Aging
#9
of 53 outputs
Altmetric has tracked 7,876,706 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 958 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,956 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.