Concurrent proton-pump inhibitors increase risk of death for lung cancer patients receiving 1st-line gefitinib treatment - a nationwide population-based study

Overview of attention for article published in Cancer Management and Research, September 2019

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质子泵抑制剂（PPIs）是用于治疗消化性溃疡常用的药物，在肿瘤患者中有20%~33% 的患者使用 PPIs 来缓解胃食管反流的症状，而在胃肠道癌症、胰腺癌、胶质母细胞瘤、胃肠道间质瘤中的使用频率更高（35%~50%）。目前临床常用的PPI包括奥美拉唑、雷贝拉…