Title |
Recovery of a 10-year-old girl from methicillin-resistant Staphylococcus aureus sepsis in response to low-dose ceftaroline treatment
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Published in |
Therapeutics and Clinical Risk Management, May 2016
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DOI | 10.2147/tcrm.s99987 |
Pubmed ID | |
Authors |
Stefan Borgmann, Beate Rieß, Thomas von Wernitz-Keibel, Matthias Bühler, Franziska Layer, Birgit Strommenger |
Abstract |
A 9-year-old girl was severely injured in a car accident in Afghanistan, in which both her lower legs were badly damaged. She was treated at the Hospital of Ingolstadt (Klinikum Ingolstadt) after she had undergone initial surgery at an Indian hospital. Various bacterial species were isolated from multiple wounds, and methicillin-resistant Staphylococcus aureus (MRSA) was one among them. After the amputation of her lower legs, she developed MRSA sepsis, which was successfully treated with a relatively low dosage of ceftaroline (Zinforo(®)/Teflaro(®); 2×9 mg/kg/d), although the bacterial isolate's minimal inhibitory concentration (1.5-4 mg/L) suggested a decreased susceptibility. In summary, ceftaroline was highly efficient and well tolerated by the patient suffering from MRSA sepsis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Brazil | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 3 | 60% |
Members of the public | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 3% |
Unknown | 30 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 5 | 16% |
Student > Master | 4 | 13% |
Researcher | 4 | 13% |
Other | 2 | 6% |
Student > Ph. D. Student | 2 | 6% |
Other | 4 | 13% |
Unknown | 10 | 32% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 10 | 32% |
Immunology and Microbiology | 3 | 10% |
Nursing and Health Professions | 3 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 3 | 10% |
Unknown | 9 | 29% |