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Emerging role of carfilzomib in treatment of relapsed and refractory lymphoid neoplasms and multiple myeloma

Overview of attention for article published in Core Evidence, April 2011
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)

Mentioned by

twitter
1 tweeter
patent
3 patents

Citations

dimensions_citation
39 Dimensions

Readers on

mendeley
43 Mendeley
Title
Emerging role of carfilzomib in treatment of relapsed and refractory lymphoid neoplasms and multiple myeloma
Published in
Core Evidence, April 2011
DOI 10.2147/ce.s13838
Pubmed ID
Authors

Salvia Jain, Diefenbach, Jasmine Zain, O'Connor

Abstract

Proteasome inhibition forms the cornerstone of antimyeloma therapy. The first-in-class proteasome inhibitor, bortezomib, either alone or in combination with other chemotherapeutic agents, induces high overall response rates and response qualities in patients with clinically and molecularly defined high-risk disease. However, resistance to bortezomib and neurotoxicity associated with the treatment remain challenging issues. Carfilzomib is a novel, well tolerated, irreversible proteasome inhibitor with minimal neurotoxicity. Carfilzomib demonstrates promising activity in myeloma patients who are refractory to bortezomib and immunomodulatory agents. This review focuses on the pharmacology, safety, and efficacy of carfilzomib for the treatment of multiple myeloma in bortezomib-naïve and bortezomib-exposed populations.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 2%
Unknown 42 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 23%
Student > Ph. D. Student 9 21%
Researcher 8 19%
Other 6 14%
Student > Master 3 7%
Other 5 12%
Unknown 2 5%
Readers by discipline Count As %
Medicine and Dentistry 11 26%
Agricultural and Biological Sciences 11 26%
Chemistry 6 14%
Biochemistry, Genetics and Molecular Biology 4 9%
Psychology 3 7%
Other 5 12%
Unknown 3 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2020.
All research outputs
#5,276,945
of 17,489,191 outputs
Outputs from Core Evidence
#23
of 67 outputs
Outputs of similar age
#38,825
of 134,242 outputs
Outputs of similar age from Core Evidence
#2
of 4 outputs
Altmetric has tracked 17,489,191 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 67 research outputs from this source. They receive a mean Attention Score of 4.5. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 134,242 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.