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Treatment simplification in HIV-infected adults as a strategy to prevent toxicity, improve adherence, quality of life and decrease healthcare costs

Overview of attention for article published in Patient preference and adherence, July 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

Mentioned by

policy
1 policy source
twitter
4 tweeters
video
1 video uploader

Citations

dimensions_citation
65 Dimensions

Readers on

mendeley
68 Mendeley
Title
Treatment simplification in HIV-infected adults as a strategy to prevent toxicity, improve adherence, quality of life and decrease healthcare costs
Published in
Patient preference and adherence, July 2011
DOI 10.2147/ppa.s22771
Pubmed ID
Authors

Jean Nachega, Mugavero, Zeier, Marco Vitoria, Joel Gallant

Abstract

Since the advent of highly active antiretroviral therapy (HAART), the treatment of human immunodeficiency virus (HIV) infection has become more potent and better tolerated. While the current treatment regimens still have limitations, they are more effective, more convenient, and less toxic than regimens used in the early HAART era, and new agents, formulations and strategies continue to be developed. Simplification of therapy is an option for many patients currently being treated with antiretroviral therapy (ART). The main goals are to reduce pill burden, improve quality of life and enhance medication adherence, while minimizing short- and long-term toxicities, reducing the risk of virologic failure and maximizing cost-effectiveness. ART simplification strategies that are currently used or are under study include the use of once-daily regimens, less toxic drugs, fixed-dose coformulations and induction-maintenance approaches. Improved adherence and persistence have been observed with the adoption of some of these strategies. The role of regimen simplification has implications not only for individual patients, but also for health care policy. With increased interest in ART regimen simplification, it is critical to study not only implications for individual tolerability, toxicity, adherence, persistence and virologic efficacy, but also cost, scalability, and potential for dissemination and implementation, such that limited human and financial resources are optimally allocated for maximal efficiency, coverage and sustainability of global HIV/AIDS treatment.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Italy 1 1%
Unknown 66 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 19%
Other 9 13%
Student > Postgraduate 9 13%
Researcher 7 10%
Student > Ph. D. Student 6 9%
Other 16 24%
Unknown 8 12%
Readers by discipline Count As %
Medicine and Dentistry 29 43%
Nursing and Health Professions 7 10%
Agricultural and Biological Sciences 3 4%
Economics, Econometrics and Finance 3 4%
Immunology and Microbiology 3 4%
Other 12 18%
Unknown 11 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2015.
All research outputs
#3,487,479
of 17,358,590 outputs
Outputs from Patient preference and adherence
#223
of 1,309 outputs
Outputs of similar age
#26,195
of 133,936 outputs
Outputs of similar age from Patient preference and adherence
#8
of 31 outputs
Altmetric has tracked 17,358,590 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,309 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 133,936 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.