| Title |
Liposomes prolong the therapeutic effect of anti-asthmatic medication via pulmonary delivery
|
|---|---|
| Published in |
International Journal of Nanomedicine, February 2012
|
| DOI | 10.2147/ijn.s28011 |
| Pubmed ID | |
| Authors |
Xiaoyu Chen, Wenhua Huang, Blenda Chi Wong, Linlin Yin, Yuen Fan Wong, Min Xu, Zhijun Yang |
| Abstract |
The main objective of this study was to develop a novel aerosolized liposome formulation for pulmonary delivery of anti-asthmatic medication and to explore the relationship between the bioavailability and anti-asthmatic efficacy of such a formulation. Asthma treatment usually requires frequent administration of medication for sustained bronchodilating response. Liposomes are known for their capability for sustained drug release and thus would be a suitable delivery system for anti-asthmatic medication for prolonged therapeutic effect. Salbutamol sulfate (SBS) was chosen as the model drug in this study because of its high water solubility and fast absorption after administration. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Argentina | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 1 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 71 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 20% |
| Student > Master | 10 | 14% |
| Researcher | 9 | 13% |
| Professor > Associate Professor | 6 | 8% |
| Student > Bachelor | 4 | 6% |
| Other | 8 | 11% |
| Unknown | 20 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 23% |
| Agricultural and Biological Sciences | 6 | 8% |
| Medicine and Dentistry | 5 | 7% |
| Biochemistry, Genetics and Molecular Biology | 4 | 6% |
| Chemistry | 3 | 4% |
| Other | 11 | 15% |
| Unknown | 26 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2021.
All research outputs
#6,438,690
of 25,584,565 outputs
Outputs from International Journal of Nanomedicine
#657
of 4,077 outputs
Outputs of similar age
#52,997
of 254,308 outputs
Outputs of similar age from International Journal of Nanomedicine
#21
of 77 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,077 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 254,308 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.