| Title |
Daptomycin approved in Japan for the treatment of methicillin-resistant Staphylococcus aureus
|
|---|---|
| Published in |
Therapeutics and Clinical Risk Management, February 2012
|
| DOI | 10.2147/tcrm.s23875 |
| Pubmed ID | |
| Authors |
Mao Hagihara, Umemura, Mori, Mikamo |
| Abstract |
Daptomycin is a lipoglycopeptide antibacterial drug that is rapidly bactericidal for methicillin-resistant Staphylococcus aureus (MRSA) infection and has antibiotic activity against a wide range of Gram-positive organisms. It has been approved by the Ministry of Health, Labor and Welfare in Japan for the treatment for bacteremia, right-sided endocarditis, and skin and skin-structure infections, such as necrotizing fasciitis, due to MRSA on the basis of a Phase III trial conducted in Japan since July, 2011. In Japanese Phase I and III trials, daptomycin therapy given at 4 mg/kg and 6 mg/kg once per day was well tolerated and effective as standard therapy for the treatment of acute bacterial skin and skin-structure infections and bacteremia caused by MRSA, but side effects remain to be evaluated in large-scale trials. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 14 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 3 | 21% |
| Student > Master | 3 | 21% |
| Researcher | 2 | 14% |
| Student > Bachelor | 1 | 7% |
| Librarian | 1 | 7% |
| Other | 2 | 14% |
| Unknown | 2 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 43% |
| Biochemistry, Genetics and Molecular Biology | 1 | 7% |
| Agricultural and Biological Sciences | 1 | 7% |
| Nursing and Health Professions | 1 | 7% |
| Immunology and Microbiology | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 3 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2012.
All research outputs
#18,310,549
of 22,671,366 outputs
Outputs from Therapeutics and Clinical Risk Management
#1,011
of 1,260 outputs
Outputs of similar age
#197,036
of 247,275 outputs
Outputs of similar age from Therapeutics and Clinical Risk Management
#8
of 10 outputs
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So far Altmetric has tracked 1,260 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
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