| Title |
Five-year follow-up of a woman with pregnancy and lactation-associated osteoporosis and vertebral fractures
|
|---|---|
| Published in |
Therapeutics and Clinical Risk Management, April 2012
|
| DOI | 10.2147/tcrm.s30668 |
| Pubmed ID | |
| Authors |
Jun Iwamoto, Yoshihiro Sato, Mitsuyoshi Uzawa, Hideo Matsumoto |
| Abstract |
We report the 5-year follow-up of a young woman who developed vertebral fractures after pregnancy and lactation and was treated with active vitamin D hormone. A 32-year-old Japanese woman consulted us because of acute lower back pain caused by L2 and L5 vertebral fractures after pregnancy and lactation. Following cessation of breast-feeding, analgesia, bed rest, and wearing of a hard brace, her lower back pain disappeared within 2 months. After 5 years of treatment with alfacalcidol 1 μg daily, the lumbar spine (L1, L3, L4) bone mineral density increased by 21.4% following vigorous reductions in bone turnover markers. No osteoporotic fractures occurred, and the vertebral fractures healed. The patient experienced no side effects, including hypercalcemia. Thus, the present case report shows long-term changes in bone turnover markers and lumbar spine bone mineral density, as well as long-term safety of alfacalcidol treatment in a young woman with pregnancy and lactation-associated osteoporosis and vertebral fractures. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 43 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 21% |
| Researcher | 5 | 12% |
| Student > Master | 4 | 9% |
| Student > Doctoral Student | 2 | 5% |
| Student > Bachelor | 2 | 5% |
| Other | 6 | 14% |
| Unknown | 15 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 33% |
| Nursing and Health Professions | 4 | 9% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Computer Science | 2 | 5% |
| Neuroscience | 2 | 5% |
| Other | 3 | 7% |
| Unknown | 15 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2012.
All research outputs
#20,823,121
of 25,584,565 outputs
Outputs from Therapeutics and Clinical Risk Management
#1,050
of 1,308 outputs
Outputs of similar age
#135,504
of 173,277 outputs
Outputs of similar age from Therapeutics and Clinical Risk Management
#5
of 6 outputs
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