Title |
Clostridium difficile outbreaks: prevention and treatment strategies
|
---|---|
Published in |
Risk Management and Healthcare Policy, July 2012
|
DOI | 10.2147/rmhp.s13053 |
Pubmed ID | |
Authors |
Fernando J Martinez, Daniel A Leffler, Ciaran P Kelly |
Abstract |
The incidence and severity of Clostridium difficile infection (CDI) have increased dramatically over the past decade. Its treatment, however, has largely remained the same with the exception of oral vancomycin use as a first-line agent in severe disease. From 1999 to 2004, 20,642 deaths were attributed to CDI in the United States, almost 7 times the rate of all other intestinal infections combined. Worldwide, several major CDI outbreaks have occurred, and many of these were associated with the NAP1 strain. This 'epidemic' strain has contributed to the rising incidence and mortality of CDI. The purpose of this article is to review the current management, treatment, infection control, and prevention strategies that are needed to combat this increasingly morbid disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 3% |
Kenya | 1 | 1% |
Unknown | 68 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 23% |
Student > Bachelor | 15 | 21% |
Other | 10 | 14% |
Researcher | 5 | 7% |
Student > Postgraduate | 5 | 7% |
Other | 13 | 18% |
Unknown | 7 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 35% |
Agricultural and Biological Sciences | 13 | 18% |
Nursing and Health Professions | 5 | 7% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Chemistry | 3 | 4% |
Other | 10 | 14% |
Unknown | 11 | 15% |