Title |
Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations
|
---|---|
Published in |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, January 2012
|
DOI | 10.2147/dmso.s15404 |
Pubmed ID | |
Authors |
J Uy, L Fogelfeld, Y Guerra |
Abstract |
We have now at our disposal the new rapid-acting insulin analogs, of which insulin lispro was the first to become commercially available. While the differences in pharmacokinetic and pharmacodynamic characteristics are indisputable, the clinical benefits attained by these changes have not been as clear. In the present review, we discuss the structure, pharmacology, and landmark studies related to insulin lispro. The clinical characteristics of insulin lispro are compared with those of insulin regular and other insulin analogs in different clinical situations. Also included are the aspects of quality of life and cost-effectiveness that may modify the modern practitioner's decision to adopt one type of insulin over another. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 2 | 6% |
Belgium | 1 | 3% |
Unknown | 30 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 6 | 18% |
Researcher | 5 | 15% |
Student > Bachelor | 4 | 12% |
Student > Doctoral Student | 2 | 6% |
Student > Postgraduate | 2 | 6% |
Other | 5 | 15% |
Unknown | 9 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 45% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 9% |
Nursing and Health Professions | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Computer Science | 1 | 3% |
Other | 1 | 3% |
Unknown | 9 | 27% |