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Current progress in the development of a prophylactic vaccine for HIV-1

Overview of attention for article published in Drug Design, Development and Therapy, December 2010
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
3 tweeters

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
55 Mendeley
Title
Current progress in the development of a prophylactic vaccine for HIV-1
Published in
Drug Design, Development and Therapy, December 2010
DOI 10.2147/dddt.s6959
Pubmed ID
Authors

Qiana Matthews

Abstract

Since its discovery and characterization in the early 1980s as a virus that attacks the immune system, there has been some success for the treatment of human immunodeficiency virus-1 (HIV-1) infection. However, due to the overwhelming public health impact of this virus, a vaccine is needed urgently. Despite the tireless efforts of scientist and clinicians, there is still no safe and effective vaccine that provides sterilizing immunity. A vaccine that provides sterilizing immunity against HIV infection remains elusive in part due to the following reasons: 1) degree of diversity of the virus, 2) ability of the virus to evade the hosts' immunity, and 3) lack of appropriate animal models in which to test vaccine candidates. There have been several attempts to stimulate the immune system to provide protection against HIV-infection. Here, we will discuss attempts that have been made to induce sterilizing immunity, including traditional vaccination attempts, induction of broadly neutralizing antibody production, DNA vaccines, and use of viral vectors. Some of these attempts show promise pending continued research efforts.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 5%
Germany 1 2%
Italy 1 2%
Brazil 1 2%
Unknown 49 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 24%
Researcher 11 20%
Student > Master 10 18%
Student > Bachelor 8 15%
Student > Postgraduate 4 7%
Other 4 7%
Unknown 5 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 49%
Medicine and Dentistry 11 20%
Biochemistry, Genetics and Molecular Biology 6 11%
Nursing and Health Professions 2 4%
Engineering 2 4%
Other 2 4%
Unknown 5 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2021.
All research outputs
#5,936,987
of 18,203,597 outputs
Outputs from Drug Design, Development and Therapy
#417
of 1,792 outputs
Outputs of similar age
#44,490
of 136,530 outputs
Outputs of similar age from Drug Design, Development and Therapy
#5
of 10 outputs
Altmetric has tracked 18,203,597 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,792 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 136,530 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.