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Asimadoline and its potential for the treatment of diarrhea-predominant irritable bowel syndrome: a review

Overview of attention for article published in Clinical and Experimental Gastroenterology, February 2012
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About this Attention Score

  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
1 tweeter
facebook
1 Facebook page

Citations

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31 Dimensions

Readers on

mendeley
25 Mendeley
Title
Asimadoline and its potential for the treatment of diarrhea-predominant irritable bowel syndrome: a review
Published in
Clinical and Experimental Gastroenterology, February 2012
DOI 10.2147/ceg.s23274
Pubmed ID
Authors

Allen Mangel, Hicks

Abstract

Irritable bowel syndrome (IBS) is a multifactorial condition with principal symptoms of pain and altered bowel function. The kappa-opioid agonist asimadoline is being evaluated in Phase III as a potential treatment for IBS. Asimadoline, to date, has shown a good safety profile and the target Phase III population - diarrhea-predominant IBS patients with at least moderate pain - was iteratively determined in a prospective manner from a Phase II dose-ranging study. The clinical data in support of this population are reviewed in this article. Furthermore, the scientific rationale for the use of asimadoline in the treatment of IBS is reviewed. Considering the high patient and societal burdens of IBS, new treatments for IBS represent therapeutic advances.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 4%
Unknown 24 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 28%
Other 5 20%
Student > Master 3 12%
Professor 2 8%
Student > Ph. D. Student 2 8%
Other 4 16%
Unknown 2 8%
Readers by discipline Count As %
Medicine and Dentistry 8 32%
Agricultural and Biological Sciences 5 20%
Chemistry 4 16%
Neuroscience 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Other 0 0%
Unknown 4 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2013.
All research outputs
#5,293,915
of 7,342,523 outputs
Outputs from Clinical and Experimental Gastroenterology
#74
of 119 outputs
Outputs of similar age
#56,122
of 91,984 outputs
Outputs of similar age from Clinical and Experimental Gastroenterology
#8
of 9 outputs
Altmetric has tracked 7,342,523 research outputs across all sources so far. This one is in the 24th percentile – i.e., 24% of other outputs scored the same or lower than it.
So far Altmetric has tracked 119 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 91,984 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.