| Title |
Incorporation of a selective sigma-2 receptor ligand enhances uptake of liposomes by multiple cancer cells
|
|---|---|
| Published in |
International Journal of Nanomedicine, August 2012
|
| DOI | 10.2147/ijn.s31981 |
| Pubmed ID | |
| Authors |
Yifei Zhang, Yixian Huang, Peng Zhang, Xiang Gao, Robert B Gibbs, Song Li |
| Abstract |
The sigma-2 receptor is an attractive target for tumor imaging and targeted therapy because it is overexpressed in multiple types of solid tumors, including prostate cancer, breast cancer, and lung cancer. SV119 is a synthetic small molecule that binds to sigma-2 receptors with high affinity and specificity. This study investigates the utility of SV119 in mediating the selective targeting of liposomal vectors in various types of cancer cells. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 3% |
| United States | 1 | 3% |
| Turkey | 1 | 3% |
| China | 1 | 3% |
| Unknown | 27 | 87% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 29% |
| Researcher | 8 | 26% |
| Student > Bachelor | 4 | 13% |
| Student > Master | 3 | 10% |
| Other | 2 | 6% |
| Other | 4 | 13% |
| Unknown | 1 | 3% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 7 | 23% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 23% |
| Agricultural and Biological Sciences | 5 | 16% |
| Medicine and Dentistry | 3 | 10% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Other | 5 | 16% |
| Unknown | 2 | 6% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2012.
All research outputs
#20,823,121
of 25,584,565 outputs
Outputs from International Journal of Nanomedicine
#3,113
of 4,077 outputs
Outputs of similar age
#140,428
of 179,468 outputs
Outputs of similar age from International Journal of Nanomedicine
#66
of 74 outputs
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So far Altmetric has tracked 4,077 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
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