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Lung inflammation caused by inhaled toxicants: a review

Overview of attention for article published in International Journal of Chronic Obstructive Pulmonary Disease, June 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

twitter
18 tweeters

Citations

dimensions_citation
89 Dimensions

Readers on

mendeley
131 Mendeley
Title
Lung inflammation caused by inhaled toxicants: a review
Published in
International Journal of Chronic Obstructive Pulmonary Disease, June 2016
DOI 10.2147/copd.s106009
Pubmed ID
Authors

John Wong, Bruce Magun, Lisa Wood

Abstract

Exposure of the lungs to airborne toxicants from different sources in the environment may lead to acute and chronic pulmonary or even systemic inflammation. Cigarette smoke is the leading cause of chronic obstructive pulmonary disease, although wood smoke in urban areas of underdeveloped countries is now recognized as a leading cause of respiratory disease. Mycotoxins from fungal spores pose an occupational risk for respiratory illness and also present a health hazard to those living in damp buildings. Microscopic airborne particulates of asbestos and silica (from building materials) and those of heavy metals (from paint) are additional sources of indoor air pollution that contributes to respiratory illness and is known to cause respiratory illness in experimental animals. Ricin in aerosolized form is a potential bioweapon that is extremely toxic yet relatively easy to produce. Although the aforementioned agents belong to different classes of toxic chemicals, their pathogenicity is similar. They induce the recruitment and activation of macrophages, activation of mitogen-activated protein kinases, inhibition of protein synthesis, and production of interleukin-1 beta. Targeting either macrophages (using nanoparticles) or the production of interleukin-1 beta (using inhibitors against protein kinases, NOD-like receptor protein-3, or P2X7) may potentially be employed to treat these types of lung inflammation without affecting the natural immune response to bacterial infections.

Twitter Demographics

The data shown below were collected from the profiles of 18 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 131 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 29 22%
Researcher 21 16%
Student > Ph. D. Student 18 14%
Student > Master 17 13%
Student > Postgraduate 5 4%
Other 20 15%
Unknown 21 16%
Readers by discipline Count As %
Medicine and Dentistry 26 20%
Biochemistry, Genetics and Molecular Biology 20 15%
Agricultural and Biological Sciences 14 11%
Pharmacology, Toxicology and Pharmaceutical Science 9 7%
Environmental Science 9 7%
Other 28 21%
Unknown 25 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 September 2019.
All research outputs
#2,020,803
of 15,942,222 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#263
of 1,861 outputs
Outputs of similar age
#42,865
of 265,514 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#13
of 89 outputs
Altmetric has tracked 15,942,222 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,861 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,514 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.