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Corneal reconstruction by stem cells and bioengineering

Overview of attention for article published in Clinical Ophthalmology, September 2012
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About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

Mentioned by

twitter
2 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
4 Dimensions

Readers on

mendeley
25 Mendeley
Title
Corneal reconstruction by stem cells and bioengineering
Published in
Clinical Ophthalmology, September 2012
DOI 10.2147/opth.s33826
Pubmed ID
Authors

Olli Arjamaa

Abstract

Almost 300 million people are visually impaired worldwide due to various eye diseases such as cataracts, glaucoma, age-related macular degeneration, diabetic retinopathy, and corneal diseases. Notably, ten million people are blind because of severe ocular surface diseases and the majority of cases occur in developing countries. Blinding ocular surface diseases have, however, become treatable by grafting of surface layers, or by full-thickness transplantation of the cornea. As the demand for human corneal tissue for surface reconstruction and transplantation far exceeds the supply, methods are being developed to supplement tissue donation. Xenotransplantation of the cornea or cells from genetically modified pigs may become one of the solutions. Transplantation of limbal stem cells within tissue biopsies, to restore the transparency of the cornea is another remarkable method, which has shown its potential in several clinical studies. The combination of stem cell technology and engineering of biocompatible tissue equivalent, still at preclinical stage, has shown us how synthetic corneal tissue is able to guide cultured corneal stromal stem cells of human origin, to become native-like stroma, the most important layer of the cornea. These findings give hope for a large-quantity production of biomaterial for corneal reconstruction. As such, clinical ophthalmologists should become more familiar with the methods of laboratory science.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 4%
Turkey 1 4%
United States 1 4%
Unknown 22 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 16%
Student > Ph. D. Student 4 16%
Student > Master 3 12%
Student > Doctoral Student 2 8%
Student > Bachelor 2 8%
Other 3 12%
Unknown 7 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 28%
Medicine and Dentistry 6 24%
Immunology and Microbiology 1 4%
Social Sciences 1 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 1 4%
Unknown 8 32%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2013.
All research outputs
#8,750,807
of 14,502,070 outputs
Outputs from Clinical Ophthalmology
#878
of 1,983 outputs
Outputs of similar age
#68,901
of 129,138 outputs
Outputs of similar age from Clinical Ophthalmology
#13
of 46 outputs
Altmetric has tracked 14,502,070 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,983 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 129,138 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.