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Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian cancer

Overview of attention for article published in International Journal of Nanomedicine, March 2012
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Citations

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Readers on

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28 Mendeley
Title
Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian cancer
Published in
International Journal of Nanomedicine, March 2012
DOI 10.2147/ijn.s29306
Pubmed ID
Authors

Wenwu Xiao, Luo, Juntao Luo, Kit Lam, Paul Henderson, Teesta Jain, John Wriggs, Harry Tseng, Douglas John Rowland, Simon Cherry

Abstract

A multifunctional telodendrimer-based micelle system was characterized for delivery of imaging and chemotherapy agents to mouse tumor xenografts. Previous optical imaging studies demonstrated qualitatively that these classes of nanoparticles, called nanomicelles, preferentially accumulate at tumor sites in mice. The research reported herein describes the detailed quantitative imaging and biodistribution profiling of nanomicelles loaded with a cargo of paclitaxel.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 4%
Portugal 1 4%
Belgium 1 4%
Unknown 25 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 25%
Researcher 6 21%
Student > Doctoral Student 4 14%
Student > Bachelor 3 11%
Student > Postgraduate 2 7%
Other 3 11%
Unknown 3 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 32%
Chemistry 4 14%
Medicine and Dentistry 4 14%
Engineering 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Other 2 7%
Unknown 5 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2012.
All research outputs
#11,056,812
of 12,438,331 outputs
Outputs from International Journal of Nanomedicine
#2,147
of 2,456 outputs
Outputs of similar age
#107,036
of 125,607 outputs
Outputs of similar age from International Journal of Nanomedicine
#33
of 43 outputs
Altmetric has tracked 12,438,331 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,456 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 125,607 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.