Title |
Cerebral blood flow in Alzheimer’s disease
|
---|---|
Published in |
Vascular Health and Risk Management, October 2012
|
DOI | 10.2147/vhrm.s34874 |
Pubmed ID | |
Authors |
Alex E Roher, Josef P Debbins, Michael Malek-Ahmadi, Kewei Chen, James G Pipe, Sharmeen Maze, Christine Belden, Chera L Maarouf, Pradeep Thiyyagura, Hua Mo, Jesse M Hunter, Tyler A Kokjohn, Douglas G Walker, Jane C Kruchowsky, Marek Belohlavek, Marwan N Sabbagh, Thomas G Beach |
Abstract |
Alzheimer's disease (AD) dementia is a consequence of heterogeneous and complex interactions of age-related neurodegeneration and vascular-associated pathologies. Evidence has accumulated that there is increased atherosclerosis/arteriosclerosis of the intracranial arteries in AD and that this may be additive or synergistic with respect to the generation of hypoxia/ischemia and cognitive dysfunction. The effectiveness of pharmacologic therapies and lifestyle modification in reducing cardiovascular disease has prompted a reconsideration of the roles that cardiovascular disease and cerebrovascular function play in the pathogenesis of dementia. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Netherlands | 1 | <1% |
Russia | 1 | <1% |
Korea, Republic of | 1 | <1% |
Unknown | 206 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 43 | 20% |
Student > Bachelor | 36 | 17% |
Researcher | 32 | 15% |
Student > Master | 18 | 9% |
Student > Postgraduate | 10 | 5% |
Other | 28 | 13% |
Unknown | 43 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 20% |
Neuroscience | 31 | 15% |
Agricultural and Biological Sciences | 20 | 10% |
Engineering | 14 | 7% |
Biochemistry, Genetics and Molecular Biology | 12 | 6% |
Other | 38 | 18% |
Unknown | 54 | 26% |