| Title |
Altered regional homogeneity in patients with unilateral acute open globe injury: a resting-state functional MRI study
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, August 2016
|
| DOI | 10.2147/ndt.s110541 |
| Pubmed ID | |
| Authors |
Xin Huang, Hai-Jun Li, Lei Ye, Ying Zhang, Rong Wei, Yu-Lin Zhong, De-Chang Peng, Yi Shao |
| Abstract |
To investigate the underlying regional homogeneity (ReHo) brain activity changes in patients with unilateral acute open-globe injury (OGI) and their relationship with their clinical features. In total, 18 patients with acute OGI (16 males and two females) and 18 healthy controls (HCs; 16 males and two females) closely matched in age, sex, and education status participated in the study. Each subject underwent a resting-state functional magnetic resonance imaging scan. The ReHo method was used to assess local features of spontaneous brain activity. Receiver-operating characteristic curve was used to distinguish OGIs from HCs. The nonparametric statistical analysis was used to explore the relationship between the observed mean ReHo values of the different brain areas and the behavioral performance. Compared with HCs, acute OGI patients had significantly increased ReHo values in the right cerebellum posterior lobe/lingual gyrus, left superior temporal gyrus/inferior frontal gyrus, left inferior frontal gyrus, left posterior cingulate cortex/precuneus, and left precentral operculum. However, there was no relationship between the observed mean ReHo values of the different brain areas and the behavioral performance. Acute OGI may cause dysfunction in many brain regions, which may reflect the underlying pathologic mechanisms of acute vision loss in OGI patients. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 1 | 9% |
| Researcher | 1 | 9% |
| Other | 1 | 9% |
| Student > Master | 1 | 9% |
| Unknown | 7 | 64% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 2 | 18% |
| Sports and Recreations | 1 | 9% |
| Medicine and Dentistry | 1 | 9% |
| Unknown | 7 | 64% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2016.
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#17,286,645
of 25,374,917 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,901
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Outputs of similar age
#252,535
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Outputs of similar age from Neuropsychiatric Disease and Treatment
#75
of 102 outputs
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