Title |
Wnt signaling pathway in retinal vascularization
|
---|---|
Published in |
Eye and Brain, August 2016
|
DOI | 10.2147/eb.s94452 |
Pubmed ID | |
Authors |
Kimberly A Drenser |
Abstract |
Wnt-signaling, a ubiquitous pathway that directs differentiation, cell polarity, and tissue specificity, has been implicated as an important gene-expression pathway in retinal development. An increasing body of evidence supports the importance of Wnt-signaling, and specifically, norrin-mediated Wnt-signaling in retinal development and retinal maintenance. Gene mutations affecting the Wnt-signaling pathways result in a variety of inherited vitreoretinopathies. Additionally, there is growing evidence that prematurity and associated retinopathy are associated with alterations in the Wnt-signaling pathways. Further investigations may allow for improved diagnoses, management, and therapies in the future. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 36 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 19% |
Researcher | 7 | 19% |
Other | 6 | 17% |
Student > Doctoral Student | 3 | 8% |
Student > Postgraduate | 2 | 6% |
Other | 6 | 17% |
Unknown | 5 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 28% |
Biochemistry, Genetics and Molecular Biology | 9 | 25% |
Agricultural and Biological Sciences | 4 | 11% |
Engineering | 2 | 6% |
Neuroscience | 2 | 6% |
Other | 4 | 11% |
Unknown | 5 | 14% |