Title |
Functions and mechanisms of long noncoding RNAs in lung cancer
|
---|---|
Published in |
OncoTargets and therapy, July 2016
|
DOI | 10.2147/ott.s109549 |
Pubmed ID | |
Authors |
Zhenzi Peng, Chunfang Zhang, Chaojun Duan |
Abstract |
Lung cancer is a heterogeneous disease, and there is a lack of adequate biomarkers for diagnosis. Long noncoding RNAs (lncRNAs) are emerging as an important set of molecules because of their roles in various key pathophysiological pathways, including cell growth, apoptosis, and metastasis. We review the current knowledge of the lncRNAs in lung cancer. In-depth analyses of lncRNAs in lung cancer have increased the number of potential effective biomarkers, thus providing options to increase the therapeutic benefit. In this review, we summarize the functions, mechanisms, and regulatory networks of lncRNAs in lung cancer, providing a basis for further research in this field. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Sweden | 1 | 6% |
Unknown | 16 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 24% |
Researcher | 4 | 24% |
Student > Ph. D. Student | 3 | 18% |
Student > Doctoral Student | 1 | 6% |
Student > Bachelor | 1 | 6% |
Other | 1 | 6% |
Unknown | 3 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 53% |
Agricultural and Biological Sciences | 2 | 12% |
Immunology and Microbiology | 1 | 6% |
Psychology | 1 | 6% |
Engineering | 1 | 6% |
Other | 0 | 0% |
Unknown | 3 | 18% |