Title |
Clinical role of ramucirumab alone or in combination with paclitaxel for gastric and gastro-oesophageal junction adenocarcinoma
|
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Published in |
OncoTargets and therapy, July 2016
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DOI | 10.2147/ott.s84153 |
Pubmed ID | |
Authors |
Michael Davidson, Elizabeth C Smyth, David Cunningham |
Abstract |
Cancers of the stomach and gastro-esophageal junction represent a significant challenge in oncology. Despite some recent advances in genetic categorization and the development of novel agents, outcomes remain poor. The vascular endothelial growth factor receptor 2 monoclonal antibody ramucirumab is the first targeted therapy to improve survival in a molecularly unselected population, and represents a valuable new treatment option. This review describes the current treatment landscape for advanced disease, evaluates existing and ongoing research into ramucirumab, and discusses its current and potential future therapeutic role. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 24% |
Other | 3 | 14% |
Researcher | 3 | 14% |
Student > Doctoral Student | 2 | 10% |
Lecturer | 2 | 10% |
Other | 1 | 5% |
Unknown | 5 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 43% |
Immunology and Microbiology | 2 | 10% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Agricultural and Biological Sciences | 1 | 5% |
Business, Management and Accounting | 1 | 5% |
Other | 2 | 10% |
Unknown | 5 | 24% |