| Title |
Hypnotic effect of the essential oil from the leaves of Myrtus communis on mice
|
|---|---|
| Published in |
Nature and science of sleep, August 2016
|
| DOI | 10.2147/nss.s101493 |
| Pubmed ID | |
| Authors |
Muluken Walle Birhanie, Bizuayehu Walle, Kidist Rebba |
| Abstract |
Myrtus communis has been suggested as a sleep aid in unconventional medicine. Moreover, previous studies have also indicated its sedative- and hypnotic-like activity. In this study, the hypnotic effect of M. communis was investigated. Essential oil (EO) of M. communis (600, 800, and 1,000 mg/kg) was given orally to Swiss albino mice of both sex, and the hypnotic effect was evaluated. In addition, the EO of M. communis (500, 600, 800, and 1,000 mg/kg) was administered orally to Swiss albino mice of both sex 60 minutes prior to pentobarbital injection (50 mg/kg). Latency to sleep and sleep duration were recorded. The effect of the EO on motor coordination and muscle relaxation was evaluated using chimney and traction tests, 60 and 90 minutes after administration of the respective doses of the EO, respectively. There was no induction of hypnosis as the presence of the righting reflex was intact. However the EO prolonged pentobarbital-induced sleeping time and there was also 50% negative response on the chimney and traction test in a dose dependent manner. The EO of M. communis did not produce a hypnotic effect, but it potentiated a hypnotic effect with significant central nervous system depressant activity. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 20 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 45% |
| Student > Bachelor | 3 | 15% |
| Other | 1 | 5% |
| Lecturer | 1 | 5% |
| Student > Doctoral Student | 1 | 5% |
| Other | 2 | 10% |
| Unknown | 3 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 15% |
| Agricultural and Biological Sciences | 2 | 10% |
| Chemistry | 2 | 10% |
| Veterinary Science and Veterinary Medicine | 1 | 5% |
| Other | 4 | 20% |
| Unknown | 4 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2016.
All research outputs
#17,432,668
of 25,576,275 outputs
Outputs from Nature and science of sleep
#446
of 633 outputs
Outputs of similar age
#253,421
of 381,680 outputs
Outputs of similar age from Nature and science of sleep
#8
of 8 outputs
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