Title |
Identification of atrophy of the subgenual anterior cingulate cortex, in particular the subcallosal area, as an effective auxiliary means of diagnosis for major depressive disorder
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Published in |
International Journal of General Medicine, August 2012
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DOI | 10.2147/ijgm.s34093 |
Pubmed ID | |
Authors |
Akira Niida, Richi Niida, Hiroshi Matsuda, Takashi Inada, Makoto Motomura, Akihiko Uechi |
Abstract |
Despite being a very common psychiatric disorder, physicians often have difficulty making a diagnosis of major depressive disorder (MDD) because, without established diagnostic criteria, they have to depend on interviews with patients and observation to assess psychiatric symptoms. However, previous researchers have reported that magnetic resonance imaging (MRI) scans identify morphological changes in the brains of patients with MDD, which inspired us to hypothesize that assessment of local changes in the brain using voxel-based morphometry would serve as an auxiliary diagnostic method for MDD. Therefore, we focused on the VSRAD(®) plus (voxel-based specific regional analysis system for Alzheimer's disease), a diagnostic support system for use in early Alzheimer's disease, which allowed us to identify regional atrophy in the brain easily based on images obtained from MRI scans. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 3% |
Japan | 1 | 3% |
Unknown | 33 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 20% |
Student > Doctoral Student | 5 | 14% |
Student > Bachelor | 4 | 11% |
Student > Ph. D. Student | 3 | 9% |
Other | 2 | 6% |
Other | 6 | 17% |
Unknown | 8 | 23% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 31% |
Neuroscience | 4 | 11% |
Agricultural and Biological Sciences | 3 | 9% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Psychology | 2 | 6% |
Other | 4 | 11% |
Unknown | 9 | 26% |