Title |
Rare synchronous association of vestibular schwannoma and indolent insular oligodendroglioma in a patient without neurofibromatosis: controversial issue of timing for surgical treatment of asymptomatic low-grade gliomas
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Published in |
OncoTargets and therapy, November 2012
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DOI | 10.2147/ott.s39276 |
Pubmed ID | |
Authors |
Maurizio Iacoangeli, Alessandro Di Rienzo, Roberto Colasanti, Lorenzo Alvaro, Niccolò Nocchi, Gabriele Polonara, Lucia Giovanna Maria Di Somma, Antonio Zizzi, Marina Scarpelli, Massimo Scerrati |
Abstract |
The co-occurrence of a vestibular schwannoma and a low-grade glioma is rare, and even rarer is the association with an oligodendroglioma. Although various authors have addressed the problem of treating patients with incidentally discovered indolent low-grade gliomas, an established protocol does not exist to date. The common approach is to reserve surgery until there is radiological evidence of tumor growth or high-grade transformation. However, because incidental low-grade glioma may represent the first stage of unavoidable pathological progression towards high-grade glioma, early and radical surgical resection should be advocated in order to increase the chance of a "cure" and prolonged survival. This case report supports this view, and suggests reflection on a possible change from a conservative philosophy to preventative surgical treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 36 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 8 | 22% |
Student > Doctoral Student | 6 | 17% |
Student > Master | 5 | 14% |
Student > Bachelor | 3 | 8% |
Other | 2 | 6% |
Other | 3 | 8% |
Unknown | 9 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 50% |
Neuroscience | 3 | 8% |
Psychology | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Social Sciences | 1 | 3% |
Other | 1 | 3% |
Unknown | 11 | 31% |