Title |
Vaginal rings for delivery of HIV microbicides
|
---|---|
Published in |
International Journal of Women's Health, November 2012
|
DOI | 10.2147/ijwh.s36282 |
Pubmed ID | |
Authors |
R Karl Malcolm, Susan M Fetherston, Clare F McCoy, Peter Boyd, Ian Major |
Abstract |
Following the successful development of long-acting steroid-releasing vaginal ring devices for the treatment of menopausal symptoms and contraception, there is now considerable interest in applying similar devices to the controlled release of microbicides against HIV. In this review article, the vaginal ring concept is first considered within the wider context of the early advances in controlled-release technology, before describing the various types of ring device available today. The remainder of the article highlights the key developments in HIV microbicide-releasing vaginal rings, with a particular focus on the dapivirine ring that is presently in late-stage clinical testing. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 75% |
Mexico | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Ireland | 2 | 2% |
United States | 2 | 2% |
United Kingdom | 1 | <1% |
Colombia | 1 | <1% |
Unknown | 119 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 33 | 26% |
Researcher | 21 | 17% |
Student > Ph. D. Student | 17 | 14% |
Student > Bachelor | 15 | 12% |
Student > Postgraduate | 9 | 7% |
Other | 15 | 12% |
Unknown | 15 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 32 | 26% |
Medicine and Dentistry | 23 | 18% |
Materials Science | 8 | 6% |
Agricultural and Biological Sciences | 7 | 6% |
Chemistry | 7 | 6% |
Other | 23 | 18% |
Unknown | 25 | 20% |