| Title |
Reproductive life events and Alzheimer’s disease in Italian women: a retrospective study
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, November 2012
|
| DOI | 10.2147/ndt.s36622 |
| Pubmed ID | |
| Authors |
Chiara Zucchella, Elena Sinforiani, Antonietta Citterio, Valentina Giarracca, Giorgio Bono, Marco Mauri |
| Abstract |
The aim of our study was to understand the complex relationship between the major reproductive life events in women with Alzheimer's disease. In a retrospective, case-control study, 275 women with Alzheimer's disease (AD) and 276 control patients from a hospital population were enrolled from July 2007 to December 2010. The AD patients presented with later menopause (P < 0.01), lower occurrence of surgical menopause (P < 0.04), reduced hormone-replacement therapy intake (P < 0.0001), and a longer reproductive life span (P < 0.01), compared to controls. No significant differences were found with respect to age at puberty, number of pregnancies, previous abortions, or contraceptive therapy. A higher education level appeared to have a protective role against the risk of developing AD. In women, menopause and hormone-replacement therapy can differentially modulate the clinical manifestations of AD, but these factors do not play a predictive role in its development. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 28 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 14% |
| Student > Ph. D. Student | 4 | 14% |
| Student > Doctoral Student | 4 | 14% |
| Other | 2 | 7% |
| Student > Bachelor | 2 | 7% |
| Other | 6 | 21% |
| Unknown | 6 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 21% |
| Psychology | 5 | 18% |
| Nursing and Health Professions | 2 | 7% |
| Neuroscience | 2 | 7% |
| Unspecified | 1 | 4% |
| Other | 3 | 11% |
| Unknown | 9 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2012.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from Neuropsychiatric Disease and Treatment
#2,584
of 3,132 outputs
Outputs of similar age
#181,455
of 202,252 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#25
of 25 outputs
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