Title |
In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
|
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Published in |
International Journal of Nanomedicine, August 2016
|
DOI | 10.2147/ijn.s113560 |
Pubmed ID | |
Authors |
Fu-Yan Lv, Rui-Hua Dong, Zhao-Jian Li, Chong-Chong Qin, Xu Yan, Xiao-Xiao He, Yu Zhou, Shi-Ying Yan, Yun-Ze Long |
Abstract |
In this work, we propose an in situ precise electrospinning of medical glue fibers onto dural wound for improving sealing capability, avoiding tissue adhesion, and saving time in dural repair. N-octyl-2-cyanoacrylate, a commercial tissue adhesive (medical glue), can be electrospun into ultrathin fibrous film with precise and homogeneous deposition by a gas-assisted electrospinning device. The self-assembled N-octyl-2-cyanoacrylate film shows high compactness and flexibility owing to its fibrous structure. Simulation experiments on egg membranes and goat meninges demonstrated that this technology can repair small membrane defects quickly and efficiently. This method may have potential application in dural repair, for example, working as an effective supplementary technique for conventional dura suture. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 3 | 75% |
Members of the public | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 3 | 19% |
Student > Doctoral Student | 2 | 13% |
Student > Bachelor | 1 | 6% |
Professor | 1 | 6% |
Unknown | 9 | 56% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 4 | 25% |
Medicine and Dentistry | 2 | 13% |
Materials Science | 1 | 6% |
Chemistry | 1 | 6% |
Unknown | 8 | 50% |