Title |
Current management options for latent tuberculosis: a review
|
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Published in |
Infection and Drug Resistance, November 2012
|
DOI | 10.2147/idr.s29180 |
Pubmed ID | |
Authors |
Brianna L Norton, David P Holland |
Abstract |
Tuberculosis remains the world's second leading infectious cause of death, with nearly one-third of the global population latently infected. Treatment of latent tuberculosis infection is a mainstay of tuberculosis-control efforts in low-to medium-incidence countries. Isoniazid monotherapy has been the standard of care for decades, but its utility is impaired by poor completion rates. However, new, shorter-course regimens using rifamycins improve completion rates and are cost-saving compared with standard isoniazid monotherapy. We review the currently available therapies for latent tuberculosis infection and their toxicities and include a brief economic comparison of the different regimens. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 1% |
Canada | 1 | 1% |
Unknown | 72 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 22% |
Researcher | 12 | 16% |
Student > Ph. D. Student | 11 | 15% |
Student > Postgraduate | 6 | 8% |
Student > Bachelor | 5 | 7% |
Other | 13 | 18% |
Unknown | 11 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 29 | 39% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 11% |
Agricultural and Biological Sciences | 8 | 11% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Immunology and Microbiology | 4 | 5% |
Other | 4 | 5% |
Unknown | 15 | 20% |