Title |
Breakthrough cancer pain – still a challenge
|
---|---|
Published in |
Journal of Pain Research, November 2012
|
DOI | 10.2147/jpr.s36428 |
Pubmed ID | |
Authors |
Cesar Margarit, Joaquim Juliá, Rafael López, Antonio Anton, Yolanda Escobar, Ana Casas, Juan Jesús Cruz, Rafael Galvez, Ana Mañas, Francisco Zaragozá |
Abstract |
Breakthrough cancer pain is defined as transient pain exacerbation in patients with stable and controlled basal pain. Although variable, the prevalence of breakthrough cancer pain is high (33%-95%). According to the American Pain Foundation, breakthrough pain is observed in 50%-90% of all hospitalized cancer patients, in 89% of all patients admitted to homes for the elderly and terminal-patient care centers, and in 35% of all ambulatory care cancer patients. The management of breakthrough cancer pain should involve an interdisciplinary and multimodal approach. The introduction of new fentanyl formulations has represented a great advance and has notably improved treatment. Among these, the pectin-based intranasal formulation adjusts very well to the profile of breakthrough pain attacks, is effective, has a good toxicity profile, and allows for convenient dosing - affording rapid and effective analgesia with the added advantage of being easily administered by caregivers when patients are unable to collaborate. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
United States | 1 | 2% |
Unknown | 60 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 15% |
Student > Ph. D. Student | 8 | 13% |
Other | 6 | 10% |
Student > Master | 6 | 10% |
Student > Bachelor | 4 | 6% |
Other | 14 | 23% |
Unknown | 15 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 45% |
Nursing and Health Professions | 4 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Agricultural and Biological Sciences | 2 | 3% |
Other | 4 | 6% |
Unknown | 19 | 31% |