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Management of achalasia

Overview of attention for article published in Clinical and Experimental Gastroenterology, February 2011
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  • Average Attention Score compared to outputs of the same age

Mentioned by

2 Facebook pages
1 Google+ user


25 Dimensions

Readers on

40 Mendeley
Management of achalasia
Published in
Clinical and Experimental Gastroenterology, February 2011
DOI 10.2147/ceg.s11593
Pubmed ID

Luca Dughera, Chiaverina M, Caciottella L, Cisaro F


Several theories on the etiology and pathophysiology of achalasia have been reported but, to date, it is widely accepted that loss of peristalsis and absence of swallow-induced relaxation of the lower esophageal sphincter are the main functional abnormalities. Treatment of achalasia often aims to alleviate the symptoms of achalasia and not to correct the underlying disorder. Medical therapy has poor efficacy, so patients who are good surgical candidates should be offered either laparoscopic myotomy or pneumatic balloon dilatation. Their own preference should be included in the decision-making process, and treatment should meet the local expertise with these procedures. Laparoscopic surgical esophagomyotomy is a safe and effective modality. It can be considered as initial management or as secondary treatment if the patient does not respond to less invasive modalities. Pneumatic dilatation has proven to be a safe, effective, and durable modality of treatment when performed by experienced individuals, and appears to be the most cost-effective alternative. For patients with multiple comorbidities and for elderly patients, who are not good surgical candidates, endoscopic injection of botulinum toxin should be considered a safe and effective procedure. However, its positive effect diminishes over time, and the need for multiple repeated sessions must be taken into consideration. In the management of patients with achalasia, nutritional aspects play an important role. When lifestyle changes are insufficient, it is necessary to proceed to percutaneous gastrostomy under radiological guidance. In the future, intraluminal myotomy or endoscopic mucosectomy will possibly be an option. Further studies are needed to investigate the role of immunosuppressive therapies in those cases in which an autoimmune etiology is suspected.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Germany 1 3%
Unknown 38 95%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 7 18%
Researcher 6 15%
Student > Master 6 15%
Student > Bachelor 5 13%
Student > Doctoral Student 3 8%
Other 8 20%
Unknown 5 13%
Readers by discipline Count As %
Medicine and Dentistry 23 57%
Nursing and Health Professions 4 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Biochemistry, Genetics and Molecular Biology 2 5%
Agricultural and Biological Sciences 2 5%
Other 2 5%
Unknown 5 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 January 2019.
All research outputs
of 14,088,520 outputs
Outputs from Clinical and Experimental Gastroenterology
of 196 outputs
Outputs of similar age
of 242,355 outputs
Outputs of similar age from Clinical and Experimental Gastroenterology
of 7 outputs
Altmetric has tracked 14,088,520 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 196 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,355 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.