| Title |
Demineralization–remineralization dynamics in teeth and bone
|
|---|---|
| Published in |
International Journal of Nanomedicine, September 2016
|
| DOI | 10.2147/ijn.s107624 |
| Pubmed ID | |
| Authors |
Ensanya Ali Abou Neel, Anas Aljabo, Adam Strange, Salwa Ibrahim, Melanie Coathup, Anne M Young, Laurent Bozec, Vivek Mudera |
| Abstract |
Biomineralization is a dynamic, complex, lifelong process by which living organisms control precipitations of inorganic nanocrystals within organic matrices to form unique hybrid biological tissues, for example, enamel, dentin, cementum, and bone. Understanding the process of mineral deposition is important for the development of treatments for mineralization-related diseases and also for the innovation and development of scaffolds. This review provides a thorough overview of the up-to-date information on the theories describing the possible mechanisms and the factors implicated as agonists and antagonists of mineralization. Then, the role of calcium and phosphate ions in the maintenance of teeth and bone health is described. Throughout the life, teeth and bone are at risk of demineralization, with particular emphasis on teeth, due to their anatomical arrangement and location. Teeth are exposed to food, drink, and the microbiota of the mouth; therefore, they have developed a high resistance to localized demineralization that is unmatched by bone. The mechanisms by which demineralization-remineralization process occurs in both teeth and bone and the new therapies/technologies that reverse demineralization or boost remineralization are also scrupulously discussed. Technologies discussed include composites with nano- and micron-sized inorganic minerals that can mimic mechanical properties of the tooth and bone in addition to promoting more natural repair of surrounding tissues. Turning these new technologies to products and practices would improve health care worldwide. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 11% |
| United Kingdom | 1 | 11% |
| Canada | 1 | 11% |
| Unknown | 6 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 44% |
| Practitioners (doctors, other healthcare professionals) | 3 | 33% |
| Scientists | 2 | 22% |
Mendeley readers
The data shown below were compiled from readership statistics for 237 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 237 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 26 | 11% |
| Student > Bachelor | 24 | 10% |
| Unspecified | 14 | 6% |
| Researcher | 14 | 6% |
| Student > Ph. D. Student | 11 | 5% |
| Other | 33 | 14% |
| Unknown | 115 | 49% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 47 | 20% |
| Unspecified | 14 | 6% |
| Biochemistry, Genetics and Molecular Biology | 8 | 3% |
| Engineering | 8 | 3% |
| Physics and Astronomy | 6 | 3% |
| Other | 33 | 14% |
| Unknown | 121 | 51% |
Attention Score in Context
This research output has an Altmetric Attention Score of 93. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2024.
All research outputs
#462,327
of 25,576,275 outputs
Outputs from International Journal of Nanomedicine
#20
of 4,142 outputs
Outputs of similar age
#8,950
of 348,941 outputs
Outputs of similar age from International Journal of Nanomedicine
#2
of 128 outputs
Altmetric has tracked 25,576,275 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,142 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 128 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.