Title |
Atorvastatin attenuates the production of IL-1β, IL-6, and TNF-α in the hippocampus of an amyloid β1-42-induced rat model of Alzheimer’s disease
|
---|---|
Published in |
Clinical Interventions in Aging, January 2013
|
DOI | 10.2147/cia.s40405 |
Pubmed ID | |
Authors |
Yuan-Yuan Zhang, Yu-Chen Fan, Min Wang, Dong Wang, Xiao-Hong Li |
Abstract |
Amyloid-beta (Aβ) peptide is reported to initiate flexible inflammation in the hippocampus of the human brain in Alzheimer's disease (AD). The present study aimed to investigate the possible effects of atorvastatin on the production of inflammation cytokines in the hippocampus and the potential impacts on behavioral ability, in an AD model. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
France | 1 | 2% |
Unknown | 54 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 21% |
Student > Ph. D. Student | 8 | 14% |
Student > Bachelor | 7 | 13% |
Professor > Associate Professor | 7 | 13% |
Researcher | 6 | 11% |
Other | 10 | 18% |
Unknown | 6 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 18% |
Agricultural and Biological Sciences | 8 | 14% |
Medicine and Dentistry | 8 | 14% |
Neuroscience | 7 | 13% |
Immunology and Microbiology | 4 | 7% |
Other | 7 | 13% |
Unknown | 12 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2024.
All research outputs
#2,811,316
of 25,374,647 outputs
Outputs from Clinical Interventions in Aging
#296
of 1,968 outputs
Outputs of similar age
#27,215
of 288,991 outputs
Outputs of similar age from Clinical Interventions in Aging
#4
of 31 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,968 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,991 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.