| Title |
TiO2 nanotube platforms for smart drug delivery: a review
|
|---|---|
| Published in |
International Journal of Nanomedicine, September 2016
|
| DOI | 10.2147/ijn.s108847 |
| Pubmed ID | |
| Authors |
Qun Wang, Jian-Ying Huang, Hua-Qiong Li, Zhong Chen, Allan Zi-Jian Zhao, Yi Wang, Ke-Qin Zhang, Hong-Tao Sun, Salem S Al-Deyab, Yue-Kun Lai |
| Abstract |
Titania nanotube (TNT) arrays are recognized as promising materials for localized drug delivery implants because of their excellent properties and facile preparation process. This review highlights the concept of localized drug delivery systems based on TNTs, considering their outstanding biocompatibility in a series of ex vivo and in vivo studies. Considering the safety of TNT implants in the host body, studies of the biocompatibility present significant importance for the clinical application of TNT implants. Toward smart TNT platforms for sustainable drug delivery, several advanced approaches were presented in this review, including controlled release triggered by temperature, light, radiofrequency magnetism, and ultrasonic stimulation. Moreover, TNT implants used in medical therapy have been demonstrated by various examples including dentistry, orthopedic implants, cardiovascular stents, and so on. Finally, a future perspective of TNTs for clinical applications is provided. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 3 | 75% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | <1% |
| Unknown | 200 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 34 | 17% |
| Student > Ph. D. Student | 28 | 14% |
| Student > Bachelor | 24 | 12% |
| Researcher | 22 | 11% |
| Student > Postgraduate | 9 | 4% |
| Other | 25 | 12% |
| Unknown | 59 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 24 | 12% |
| Materials Science | 22 | 11% |
| Chemistry | 21 | 10% |
| Medicine and Dentistry | 16 | 8% |
| Biochemistry, Genetics and Molecular Biology | 11 | 5% |
| Other | 32 | 16% |
| Unknown | 75 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2016.
All research outputs
#16,047,334
of 25,373,627 outputs
Outputs from International Journal of Nanomedicine
#1,887
of 4,123 outputs
Outputs of similar age
#207,585
of 348,369 outputs
Outputs of similar age from International Journal of Nanomedicine
#63
of 128 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,123 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
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We're also able to compare this research output to 128 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.