| Title |
Changes in behavior as side effects in methylphenidate treatment: review of the literature
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, October 2016
|
| DOI | 10.2147/ndt.s114185 |
| Pubmed ID | |
| Authors |
Doris Susanne Konrad-Bindl, Ursula Gresser, Barbara Maria Richartz |
| Abstract |
Our review of the scientific literature focused on an analysis of studies describing instances of methylphenidate treatment leading (or not) to behavioral changes in the pediatric, adolescent, and adult populations. We conducted a literature search in PubMed, Medline, and Google using the keywords "methylphenidate", "behavioral changes", "adverse effects", and "side effects". A total of 44 studies were identified as reporting on the effects and adverse effects of methylphenidate administration, and were included in the analysis. Five studies specifically set out to study, record, and discuss changes in behavior. Eight studies did not set out to study behavioral effects, but record and discuss them. A total of 28 studies recorded behavioral effects, but failed to discuss these further. Three studies did not include behavioral effects. This review records what data have been published in respect of changes in behavior in association with the use of methylphenidate. While there is some evidence to suggest that methylphenidate causes changes in behavior, the majority of the studies reviewed paid little or no attention to this issue. Based on the available data, it is impossible to determine the point at which such behavioral effects occur. The frequency of occurrence of behavioral effects is also impossible to determine with certainty. Based on the available data, it is not possible to rule out whether behavioral effects may persist or not persist once treatment is discontinued. In conclusion, despite countless publications and extensive administration, especially to children, we have insufficient data to judge the long-term effects and risks of methylphenidate taking. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 71% |
| Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 1% |
| Unknown | 81 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 12 | 15% |
| Student > Ph. D. Student | 11 | 13% |
| Student > Master | 11 | 13% |
| Student > Doctoral Student | 6 | 7% |
| Student > Postgraduate | 6 | 7% |
| Other | 16 | 20% |
| Unknown | 20 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 23% |
| Psychology | 15 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 9% |
| Social Sciences | 5 | 6% |
| Neuroscience | 4 | 5% |
| Other | 11 | 13% |
| Unknown | 21 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2023.
All research outputs
#1,659,752
of 25,394,764 outputs
Outputs from Neuropsychiatric Disease and Treatment
#210
of 3,131 outputs
Outputs of similar age
#29,302
of 332,682 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#10
of 88 outputs
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