Title |
Management of noninfectious posterior uveitis with intravitreal drug therapy
|
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Published in |
Clinical Ophthalmology, October 2016
|
DOI | 10.2147/opth.s89341 |
Pubmed ID | |
Authors |
Hui Yi Tan, Aniruddha Agarwal, Cecilia S Lee, Jay Chhablani, Vishali Gupta, Manoj Khatri, Jayabalan Nirmal, Carlos Pavesio, Rupesh Agrawal |
Abstract |
Uveitis is an important cause of vision loss worldwide due to its sight-threatening complications, especially cystoid macular edema, as well as choroidal neovascularization, macular ischemia, cataract, and glaucoma. Systemic corticosteroids are the mainstay of therapy for noninfectious posterior uveitis; however, various systemic side effects can occur. Intravitreal medication achieves a therapeutic level in the vitreous while minimizing systemic complications and is thus used as an exciting alternative. Corticosteroids, antivascular endothelial growth factors, immunomodulators such as methotrexate and sirolimus, and nonsteroidal anti-inflammatory drugs are currently available for intravitreal therapy. This article reviews the existing literature for efficacy and safety of these various options for intravitreal drug therapy for the management of noninfectious uveitis (mainly intermediate, posterior, and panuveitis). |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 55 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 18% |
Researcher | 7 | 13% |
Student > Ph. D. Student | 6 | 11% |
Student > Bachelor | 4 | 7% |
Other | 4 | 7% |
Other | 11 | 20% |
Unknown | 13 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 49% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 9% |
Nursing and Health Professions | 3 | 5% |
Computer Science | 2 | 4% |
Chemical Engineering | 1 | 2% |
Other | 3 | 5% |
Unknown | 14 | 25% |