Title |
Biomarkers in critical illness: have we made progress?
|
---|---|
Published in |
International Journal of Nephrology and Renovascular Disease, October 2016
|
DOI | 10.2147/ijnrd.s113219 |
Pubmed ID | |
Authors |
Patrick M Honore, Rita Jacobs, Inne Hendrickx, Elisabeth De Waele, Viola Van Gorp, Olivier Joannes-Boyau, Jouke De Regt, Willem Boer, Herbert D Spapen |
Abstract |
Biomarkers have emerged as exemplary key players in translational medicine. Many have been assessed for timely recognition, early treatment, and adequate follow-up for a variety of pathologies. Biomarker sensitivity has improved considerably over the last years but specificity remains poor, in particular when two "marker-sensitive" conditions overlap in one patient. Biomarker research holds an enormous potential for diagnostic and prognostic purposes in postoperative and critically ill patients who present varying degrees of inflammation, infection, and concomitant (sub)acute organ dysfunction or failure. Despite a remarkable progress in development and testing, biomarkers are not yet ready for routine use at the bedside. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 3% |
Unknown | 33 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 29% |
Student > Ph. D. Student | 5 | 15% |
Student > Postgraduate | 4 | 12% |
Student > Bachelor | 3 | 9% |
Researcher | 3 | 9% |
Other | 7 | 21% |
Unknown | 2 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 62% |
Nursing and Health Professions | 2 | 6% |
Agricultural and Biological Sciences | 2 | 6% |
Computer Science | 1 | 3% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 2 | 6% |
Unknown | 5 | 15% |