Title |
The therapeutic efficacy of propranolol in children with recurrent primary epistaxis
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Published in |
Drug Design, Development and Therapy, March 2013
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DOI | 10.2147/dddt.s41756 |
Pubmed ID | |
Authors |
Bojko Bjelakovic, Mila Bojanovic, Stevo Lukic, Ljiljana Saranac, Vladislav Vukomanovic, Sergej Prijic, Nikola Zivkovic, Dusica Randjelovic |
Abstract |
We hypothesized that some characteristics of beta-blockers, including negative inotropic, peripheral vasoconstrictor, and antiangiogenic effects, might be potentially useful in treating children with epistaxis. From June 2010 to March 2012, a total of seven children with recurrent primary epistaxis resistant to conventional management were observed at our institution. An overall effectiveness of propranolol was noted in all seven children when given a dose of 1.5-2 mg/kg/day (divided into three doses) as a second line therapy for terminating epistaxis. Based on our first experience, we believe that propranolol could be a favorable treatment option for patients with primary epistaxis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 1 | 5% |
Unknown | 18 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 3 | 16% |
Student > Postgraduate | 3 | 16% |
Student > Doctoral Student | 2 | 11% |
Researcher | 2 | 11% |
Professor > Associate Professor | 2 | 11% |
Other | 4 | 21% |
Unknown | 3 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 37% |
Biochemistry, Genetics and Molecular Biology | 3 | 16% |
Agricultural and Biological Sciences | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Social Sciences | 1 | 5% |
Other | 1 | 5% |
Unknown | 5 | 26% |