Title |
Weekly paclitaxel, gemcitabine, and external irradiation followed by randomized farnesyl transferase inhibitor R115777 for locally advanced pancreatic cancer
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Published in |
OncoTargets and therapy, August 2012
|
DOI | 10.2147/ott.s33560 |
Pubmed ID | |
Authors |
Tyvin A Rich, Kathryn Winter, Howard Safran, John P Hoffman, Beth Erickson, Pramila R Anne, Robert J Myerson, Vivian JM Cline-Burkhardt, Kimberly Perez, Christopher Willett |
Abstract |
The Radiation Therapy Oncology Group (RTOG) multi-institutional Phase II study 98-12, evaluating paclitaxel and concurrent radiation (RT) for locally advanced pancreatic cancer, demonstrated a median survival of 11.3 months and a 1-year survival of 43%. The purpose of the randomized Phase II study by RTOG 0020 was to evaluate the addition of weekly low- dose gemcitabine with concurrent paclitaxel/RT and to evaluate the efficacy and safety of the farnesyl transferase inhibitor R115777 following chemoradiation. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 48 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 25% |
Student > Master | 7 | 15% |
Student > Bachelor | 4 | 8% |
Other | 2 | 4% |
Professor | 2 | 4% |
Other | 8 | 17% |
Unknown | 13 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 40% |
Agricultural and Biological Sciences | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Veterinary Science and Veterinary Medicine | 1 | 2% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Other | 6 | 13% |
Unknown | 17 | 35% |