| Title |
Prevalence, putative mechanisms, and current management of sleep problems during chemotherapy for cancer
|
|---|---|
| Published in |
Nature and science of sleep, December 2012
|
| DOI | 10.2147/nss.s18895 |
| Pubmed ID | |
| Authors |
Oxana Palesh, Luke Peppone, Pasquale F Innominato, Michelle Janelsins, Monica Jeong, Lisa Sprod, Josee Savard, Max Rotatori, Shelli Kesler, Melinda Telli, Karen Mustian |
| Abstract |
Sleep problems are highly prevalent in cancer patients undergoing chemotherapy. This article reviews existing evidence on etiology, associated symptoms, and management of sleep problems associated with chemotherapy treatment during cancer. It also discusses limitations and methodological issues of current research. The existing literature suggests that subjectively and objectively measured sleep problems are the highest during the chemotherapy phase of cancer treatments. A possibly involved mechanism reviewed here includes the rise in the circulating proinflammatory cytokines and the associated disruption in circadian rhythm in the development and maintenance of sleep dysregulation in cancer patients during chemotherapy. Various approaches to the management of sleep problems during chemotherapy are discussed with behavioral intervention showing promise. Exercise, including yoga, also appear to be effective and safe at least for subclinical levels of sleep problems in cancer patients. Numerous challenges are associated with conducting research on sleep in cancer patients during chemotherapy treatments and they are discussed in this review. Dedicated intervention trials, methodologically sound and sufficiently powered, are needed to test current and novel treatments of sleep problems in cancer patients receiving chemotherapy. Optimal management of sleep problems in patients with cancer receiving treatment may improve not only the well-being of patients, but also their prognosis given the emerging experimental and clinical evidence suggesting that sleep disruption might adversely impact treatment and recovery from cancer. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| France | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 100 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 13% |
| Student > Ph. D. Student | 12 | 12% |
| Student > Doctoral Student | 10 | 10% |
| Other | 9 | 9% |
| Student > Bachelor | 9 | 9% |
| Other | 23 | 22% |
| Unknown | 27 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 19% |
| Psychology | 19 | 18% |
| Nursing and Health Professions | 11 | 11% |
| Sports and Recreations | 6 | 6% |
| Social Sciences | 3 | 3% |
| Other | 13 | 13% |
| Unknown | 31 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2021.
All research outputs
#3,583,518
of 25,374,917 outputs
Outputs from Nature and science of sleep
#172
of 629 outputs
Outputs of similar age
#33,645
of 285,750 outputs
Outputs of similar age from Nature and science of sleep
#1
of 3 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 629 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one has gotten more attention than average, scoring higher than 72% of its peers.
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