Title |
Novel therapeutic strategies for patients with triple-negative breast cancer
|
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Published in |
OncoTargets and therapy, October 2016
|
DOI | 10.2147/ott.s105716 |
Pubmed ID | |
Authors |
Jun-Fei Zhang, Jia Liu, Yu Wang, Bin Zhang |
Abstract |
Triple-negative breast cancer (TNBC) represents a very heterogeneous group of breast diseases. Currently, the backbone of therapy for TNBC is mainly chemotherapy as there are no effective specific targeted agents approved to treat TNBC. Despite initial responses to chemotherapy, resistance frequently and rapidly develops and metastatic TNBC has a poor prognosis. Therefore, new targeted strategies are, accordingly, urgently needed. This article discusses the recent developments in targeted agents explored for TNBC, aiming to offer novel therapeutic strategies that can potentially assist in designing personalized therapeutics in the future as well as provide the basis for further research in an attempt to target TNBC. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Uruguay | 1 | 2% |
Unknown | 45 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 10 | 22% |
Student > Bachelor | 6 | 13% |
Student > Master | 6 | 13% |
Researcher | 4 | 9% |
Other | 4 | 9% |
Other | 7 | 15% |
Unknown | 9 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 24% |
Biochemistry, Genetics and Molecular Biology | 8 | 17% |
Agricultural and Biological Sciences | 6 | 13% |
Nursing and Health Professions | 3 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Other | 5 | 11% |
Unknown | 11 | 24% |